Canvax Apelin Receptor G0511-B
PART NO: CX-G0511-B
Apelin Receptor, ExpressMAX™ Human GPCR ORF Clones
Apelin Receptor (APLNR, APJ) is a GPCR with considerable sequence homology to the angiotensin Receptor, which is actually an apelin Receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. Its predominant endogenous ligands are apelin-36, apelin-13 and [Pyr1]-apelin-13. APLNR Receptor and apelin peptides act as mediators of cardiovascular and Central Nervous System functions, fluid homeostasis, adipocyte endocrine secretion, glucose metabolism, in embryonic and tumor angiogenesis and as a HIV-1 co-receptor.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Apelin Receptor (APLNR, APJ) is a GPCR with considerable sequence homology to the angiotensin Receptor, which is actually an apelin Receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. Its predominant endogenous ligands are apelin-36, apelin-13 and [Pyr1]-apelin-13. APLNR Receptor and apelin peptides act as mediators of cardiovascular and Central Nervous System functions, fluid homeostasis, adipocyte endocrine secretion, glucose metabolism, in embryonic and tumor angiogenesis and as a HIV-1 co-receptor.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Format: 15 µL Shipping conditions: Dry Ice Storage Conditions: -20 ºC | |
Manufacturer | Canvax |
Manufacturer P/n | G0511 - B |