Canvax Galanin Receptor 1 G0559-A

Galanin Receptor 1, ExpressMAX™ Human GPCR ORF Clones

Galanin Receptor 1 is a member of the GPCR family, or metabotropic receptor and is encoded in Humans by the GAL1R gene. The neuropeptide galanin is ligand of this receptor and participates in a wide range of biological effects. GALR1 inhibits adenylyl cyclase via Gi/Go protein. It is expressed in the brain, spinal cord, small intestine and heart. Selective galanin agonists are anticonvulsant, while antagonists produce antidepressant and anxiolytic effects in animals, so these ligands for the galanin receptors may be potentially therapeutic compounds in Humans.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).