Canvax G protein-coupled Receptor 119 G0595-Plus

G protein-coupled Receptor 119, ExpressMAX™ Human GPCR ORF Clones

G protein-coupled Receptor 119 is encoded in Humans by the GPR119 gene. It is a member of the rhodopsin subfamily GPCRthat is expressed in the pancreas and gastrointestinal tract. It is activated by lipid amides including lysophosphatidyl-choline and oleoylethanolamide and may be involved in glucose homeostasis through modulation of insulin secretion. GPR119 is target in the treatment of type 2 diabetes and obesity.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).