Canvax Serotonin Receptor 1B G0612-A

Serotonin Receptor 1B, ExpressMAX™ Human GPCR ORF Clones

Serotonin Receptor 1B is a member of the GPCR family, coupled to guanine nucleotide-binding proteins that inhibits adenylate cyclase activity. In Humans, it is encoded by the HTR1B gene. This is one of the different receptors for serotonin, a biogenic hormone that functions as a neurotransmitter, as hormone and as mitogen. HTR1B is located in the basal ganglia, striatum, hippocampus and vascular smooth muscle and plays a role in thermoregulation, respiration, appetite control, sexual behavior, aggression and anxiety.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).