Canvax Adrenergic ADRB2 G0505-Plus
PART NO: CX-G0505-PLUS
Adrenergic ADRB2, ExpressMAX™ Human GPCR ORF Clones
Beta-2-adrenergic Receptor is a member of beta adrenergic Receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. It is located primarily in the CNS, heart, kidney and muscle where it is involved in smooth muscle relaxation (e.g. bronchodilation). ADRB2 is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. Different polymorphic forms, point mutations and/or downregulation of the gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Beta-2-adrenergic Receptor is a member of beta adrenergic Receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. It is located primarily in the CNS, heart, kidney and muscle where it is involved in smooth muscle relaxation (e.g. bronchodilation). ADRB2 is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. Different polymorphic forms, point mutations and/or downregulation of the gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Format: 15 µL + 0.2 mL Shipping conditions: Dry Ice Storage Conditions: -20 ºC | |
Manufacturer | Canvax |
Manufacturer P/n | G0505 - Plus |