Canvax Cannabinoid 2 Receptor G0517-A
PART NO: CX-G0517-A
Cannabinoid 2 Receptor, ExpressMAX™ Human GPCR ORF Clones
Cannabinoid 2 Receptor inhibits adenylate cyclase activity through their Gi/Gao subunits in a dose dependent for its ligand. The principal endogenous ligand for the CNR2 receptor is 2-archidonoylglycerol. Through their Gß? subunits, CNR2 Receptor is coupled to the MAPK-ERK pathway, which regulates cellular processes in both mature and developing tissues. It is localized on immune cells such as monocytes, macrophages, B-cells and T-cells. It is also found in the brain, on microglia but not in neurons and the gastrointestinal system, where it modulates intestinal inflammatory response.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Cannabinoid 2 Receptor inhibits adenylate cyclase activity through their Gi/Gao subunits in a dose dependent for its ligand. The principal endogenous ligand for the CNR2 receptor is 2-archidonoylglycerol. Through their Gß? subunits, CNR2 Receptor is coupled to the MAPK-ERK pathway, which regulates cellular processes in both mature and developing tissues. It is localized on immune cells such as monocytes, macrophages, B-cells and T-cells. It is also found in the brain, on microglia but not in neurons and the gastrointestinal system, where it modulates intestinal inflammatory response.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Format: 15 µL Shipping conditions: Dry Ice Storage Conditions: -20 ºC | |
Manufacturer | Canvax |
Manufacturer P/n | G0517 - A |