Canvax Chemokine CX3CR1 G0534-Plus

Chemokine CX3CR1, ExpressMAX™ Human GPCR ORF Clones

CX3CR1 binds the chemokine CX3CL1 (also known neurotactin or fractalkine). Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. CX3CR1 is a coreceptor for HIV-1 and it is expressed by lymphocytes and monocytes and plays major role in the survival of monocytes. Also this GPCR is important in the migration of microglia in the Central Nervous Systems to their synaptic targets, where phagocytosis and synapsis occur.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).