Canvax Human Calcineurin Heterodimer (PPP3CA & PPP3R1), GST tag removed PR0483

Human Calcineurin Heterodimer (PPP3CA & PPP3R1), GST tag removed, high quality recombinant protein with proven performance in elisa, wb, ab production or protein array

Is a calcium and calmodulin dependent serine/threonine protein phosphatase. Calcineurin activates nuclear factor of activated T cell, cytoplasmic (NFATc), a transcription factor, by dephosphorylating it. The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2 (IL-2), which, in turn, stimulates the growth and differentiation of T cell response. Calcineurin is the target of a class of drugs called calcineurin inhibitors, which includes cyclosporine, pimecrolimus and tacrolimus.

Main Features:

Highest purity: free of interferences from other proteins or contaminants. Convenient: available in different sizes and tags. Cost avoidance: dry ice free of charge.

Includes: Includes for 50 µg: - 50 µg Recombinant Protein

Applications: ELISA. Western Blot. Antibody Production. Protein array.