Geneticin G418 Crystalline Bioconcept 4-15P01-GA

Used as a selective agent in mammalian cells at concentrations ranging from 400 to 1000 µg/ml. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. Resistance to G418 is conferred by the Neomycin resistance gene (neo) from Tn5 encoding an aminoglycoside 3'-phosphotransferase, APH 3' II.