Campylobacter Agar Base (Preston) 1131 Condalab

Campylobacter Agar Base (Preston) is based on the formulation described by Bolton and Robertson. It was designed for the isolation of Campylobacter species from human, animal, bird, and environmental samples. The supplement is especially selective for Campylobacter jejuni and C. coli. The recovery of injured cells can be improved by pre-enrichment in broth medium, permitting sublethal injured organisms to repair lesions and to tolerate certain selective antibiotics. Campylobacter spp. are of worldwide significance in human and animal disease, especially C. jejuni, considered one of the main causes of acute bacterial diarrhoea.

Casein peptone and Soy peptone provide nitrogen, vitamins, minerals, and amino acids essential for growth. Sodium chloride supplies essential electrolytes for transport and osmotic balance. Polymyxin B inhibits Gram-negative microorganisms. Cycloheximide inhibits yeasts. Rifampicin inhibits Gram-positive organisms. Trimethoprim exerts its antibacterial action through the selective inhibition of bacterial dihydrofolate reductase (DHFR), which is an essential enzyme in all living cells. Bacteriological agar is the solidifying agent.